The Effect of Mixed Exercise and Metabolic Stress in Relationship to Age in Healthy Men
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
Aging in men reduces the amount of luteinizing hormone (LH) and testosterone (Te) secreted in
each burst. Stress-associated mechanisms introduced by acute illness and chronic disease
decrease LH and Te secretion further. A major unresolved issue is whether the aging process
heightens the negative effects of a stressor (whether physical or metabolic) upon LH and Te
secretion. This study will assess LH and Te secretion in response to a physical stressor
(maximal exercise) and a common metabolic stressor (hyperglycemia) as a function of age in
healthy men ages 18-80 yr.