The Effect of Midazolam on Fluid Responsiveness in Septic Patients
Status:
Completed
Trial end date:
2013-04-01
Target enrollment:
Participant gender:
Summary
Fluid resuscitation remains the foundation for septic treatment.The evaluation of fluid
responsiveness has significance in volume resuscitation for septic shock patients. As the
sedative which is commonly used in ICU, Midazolam is supposed to change fluid responsiveness
for the pharmacological effect of venodilation. However, the hypothesis has not been
certified clinically. In this research, the investigators aim to test the hypothesis that
Midazolam can increase fluid responsiveness(using passive leg raising test) in septic shock
patients.