The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis
Status:
Completed
Trial end date:
2023-10-20
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to assess the effect of melatonin on MDA serum, IL-6, IL-8
levels, ANC, and sepsis score in preterm neonates with sepsis. The main question aim to
answer :
• Does melatonin affect MDA serum, IL-6, IL-8 levels, ANC, and sepsis score in preterm
neonates with sepsis?
The participants in the treatment group will receive a single dose of oral melatonin 20 mg,
meanwhile those the control group will receive placebo.
The researchers will compare MDA serum, IL-6, IL-8 levels, ANC, and sepsis score before and
after receiving melatonin, whether there are decreases of MDA serum, IL-6, IL-8 levels, ANC
and increase of sepsis score