Overview

The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome

Status:
Completed

Trial end date:
2018-07-20

Target enrollment:

Participant gender:

Summary

The objective of the study is to investigate whether prophylactic treatment with melatonin has an effect on depressive symptoms. Secondarily melatonin's effect on anxiety, sleep and circadian disturbances will be investigated. The MEDACIS trial is a randomised, placebo-controlled, double-blinded multicenter trial investigating the effect of 25 mg exogenous melatonin (intervention group) against placebo (control group) and the study is designed as a parallel group superiority trial.

Phase:

Phase 2/Phase 3

Details

Lead Sponsor:

Zealand University Hospital

Collaborators:

Pharma Nord
Psychiatric Research Unit, Region Zealand, Denmark
University of Copenhagen

Treatments:

Melatonin