Overview The Effect of Losartan and Losartan Plus Isosorbide Mononitrate on Central Blood Pressure Measurements (0954-317) Status: Completed Trial end date: 2006-12-01 Target enrollment: Participant gender: Summary This study will qualify a functional model that can measure central blood pressure and vascular compliance effects through noninvasive means. Phase: Phase 1 Details Lead Sponsor: Merck Sharp & Dohme Corp.Treatments: IsosorbideIsosorbide DinitrateIsosorbide-5-mononitrateLosartan