The Effect of Levetiracetam on the Postmastectomy Pain Syndrome

• Status: Completed
• Trial end date: 2006-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is determine whether or not the antiepileptic drug Levetiracetam is an effective treatment of the postmastectomy pain syndrome.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Odense University Hospital
• Treatments: Etiracetam; Levetiracetam; Piracetam

Criteria

Inclusion Criteria:

• Symptoms characteristic for postmastectomy pain syndrome with a duration of more than 3 months and at least 6 months after the operation.

• Neuropathic pain diagnose confirmed by abnormities in the neurological investigation and/or psychophysical sensory testing

• Average (1 week) pain score minimum 4 on a 11 points numerical rating scale for total pain.

• Pain present minimum 4 out of 7 days.

• Fertile women must use anticonception.

Exclusion Criteria:

• Verified og suspected other reason than mastectomy/lumpectomy for the pain.

• Known allergic effects to levetiracetam.

• Known sideeffects to treatment with levetiracetam.

• Pregnancy or breast-feeding.

• Severe disease (terminal cancer, heart failure, kidney insufficiency, severe respiratory problems)

• Compliance problems