The Effect of Ketamine on Postoperative Cognitive Dysfunction.
Status:
Recruiting
Trial end date:
2021-10-01
Target enrollment:
Participant gender:
Summary
Available evidence suggests that there is no significant difference in the incidence of
postoperative cognitive dysfunction POCD when general anaesthesia and regional anaesthesia
are compared[13, 14]. To the knowledge of the investigators , no studies are examining the
effects of ketamine on cognitive outcomes in the setting of spinal anesthesia.
Thus, the purpose of this study was to compare the cognitive status, as assessed by the
SPMSQ, of elderly patients undergoing orthopaedic surgery under spinal anaesthesia before and
after ketamine administration. The authors hypothesized that patients receiving ketamine
would exhibit better cognitive performance.