The Effect of Irrigant Types Used During Endodontic Treatment on Postoperative Pain
Status:
Unknown status
Trial end date:
2019-12-30
Target enrollment:
Participant gender:
Summary
Chemomechanical preparation of the root canal system potentially results in extrusion of
debris into the periradicular tissues. This debris is composed of hard tissue (dentin), soft
tissue (inflamed or necrotic pulp tissues) and microbiota. Furthermore, the chemical adjuncts
used during root canal disinfection may also extrude into the periradicular tissues.
Extrusion of such materials results in postoperative pain, inflammation and and flare-up.
There is evidence to demonstrate that most instrumentation techniques cause extrusion of
debris, and that, severity of the inflammatory response depends on the amount of debris
extrusion. Several factors may influence the debris extrusion during root canal preparation,
including the instrument design, technique of use and irrigating agent used during
preparation.Sodium hypochlorite (NaOCl) is the most commonly used root canal irrigant during
root canal treatment. However, its cytotoxic effects when extruded into the periapical
tissues is an issue of clinical concern. Thus, there has been a search for more biocompatible
irrigants. One potential option, which has not been explored in detail, is the use of NaOCl,
but in a gel form rather than a solution. NaOCl gel has similar effects on the dentin, as the
solution form. Interestingly, greater dentinal tubule penetration depth has been reported for
the gel form, compared to the solution. Previous studies have evaluated the effect of
preparation techniques, the number of appointments and intracranial medicaments on
postoperative pain during Endodontics treatment. There is no study evaluating the effect of
different irritant type on PP. Therefore, this study will be evaluated the effect of
different irritant type (gel or solution form of NaOCI) on postoperative pain.