The Effect of Intravenous Lidocaine on Allodynia

• Status: Completed
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to study if lidocaine, given intravenously, reduces pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alabama at Birmingham
• Collaborator: American Society of Regional Anesthesia
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Chronic Regional Pain Syndrome diagnostic criteria by the Work Safe BC. vi

Exclusion Criteria:

• History of Substance abuse

• Other Medications: CRPS patients are expected to be treated for chronic pain, whether the current treatment regimen interferes with sensory motor testing will be determined on a case by case basis.

• Coronary Artery Disease (CAD): unstable

• Congestive Heart Failure (CHF): unstable

• Heart Arrhythmia: symptomatic

• Chronic Obstructive Pulmonary Disease (COPD)

• Lidocaine Allergy

• Diagnostic and Statistical Manual of Mental Disorders (Rev IV): Axis I: Common Axis I disorders include depression, anxiety disorders, bipolar disorder, ADHD, and schizophrenia. Axis II: borderline personality disorder, schizotypal personality disorder, antisocial personality disorder, and mild mental retardation.

• Presence of Contraindications for MRI

• Presence of electronically, magnetically, and mechanically activated implants

• Electronically, magnetically, and mechanically activated implants

• Ferromagnetic or electronically operated active devices like automatic cardioverter defibrillators

• Cardiac pacemakers

• Metallic splinters in the eye

• Ferromagnetic haemostatic clips in the central nervous system (CNS)

• Claustrophobia

• Pregnancy