The Effect of Intranasal Oxytocin on Pain Sensitivity and Threshold
Status:
Unknown status
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
Oxytocin is neurohypophysial peptide that acts mainly as a neuromodulator in the brain.The
vast majority of basic science studies suggested a large effect of oxytocin in minimizing
acute pain.Few studies have demonstrated an association between plasma levels of oxytocin and
pain in humans. Since addictive properties of oxytocin have not been described, the drug may
have important application in the management of acute and chronic pain. No studies have
examined the effect of intranasal oxytocin on pain sensitivity and threshold.