The Effect of Intranasal Insulin on Hepatic and Intestinal Triglyceride-rich Lipoprotein Production
Status:
Completed
Trial end date:
2017-04-26
Target enrollment:
Participant gender:
Summary
This study compares the effect of insulin given as a nasal spray with a placebo. Insulin is a
chemical messenger (hormone) in the body that controls fat (triglyceride) levels in the blood
by controlling the amount of fat made by the liver and gut. Recent research suggests that
insulin may work through the brain. The investigators hypothesize that preferential delivery
of insulin into the brain, through nasal spray of the hormone, may affect the amount of fats
made by the liver and gut.