The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy
Status:
COMPLETED
Trial end date:
2025-04-08
Target enrollment:
Participant gender:
Summary
The goal of this randomized double blind study is to compare the effects of hyoscine-n-butylbromide, and ondansetron on postoperative nausea-vomiting, and pain in patients who underwent laparoscopic cholecystectomy.The main questions it aims to answer are:
1\. Is antiemetic properties of hyoscine-n-butylbromide effective after laparoscopic cholecyctectomy?
1\. Does hyoscine-n-butylbromide have valuable effects on postoperative pain after laparoscopic cholecyctectomy?
Participants will be the paients undergoing laparoscopic cholecyctectomy.
The patients participating in the study were randomized into two groups as Group-HBB, and Group-O.
After the gallbladder removed, IV infusion of 1000 mg paracetamol, and 1.5 mg/kg tramadol will administered to the patients. 20 mg hyoscine-n-butylbromide in 100 ml saline will administered to the patients in Group-HBB, and 4 mg ondansetron infusion in 100 ml saline will be administered to the patients in Group-O.
Postoperative nausea and vomitting score and pain intensity and rescue drugs will be recorded in postoperative 24 hours.