The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trial
Status:
Not yet recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
The primary research question: In critically ill patients with nutrition 'risk factors', what
is the effect of providing combined EN/PN to the group prescribed a higher dose (≥2.2
grams/kg/day) of protein/amino acid administration compared to a low group prescribed ≤1.2
gram/kg/day (EN only) on patient's functional recovery as measured by 6-minute walk distance
just prior to hospital discharge? The hypothesis: Compared to a control group reflective of
usual care prescribing practices and an EN only approach, the administration of a higher dose
protein/amino acids using EN and PN to nutritionally high-risk critically ill patients will
be associated with improved functional outcome.
Phase:
Phase 3
Details
Lead Sponsor:
RWTH Aachen University
Collaborator:
Clinical Evaluation Research Unit at Kingston General Hospital