The Effect of High Volume Injection With and Without Steroid in Chronic Achilles Tendinopathy

• Status: Completed
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

The aim of the study is to determine the effect of steroid in High Volume Injection (HVI) compared to HVI without steroid (volume effect) in functional outcomes and ultrasound tendon thickness and Color Doppler activity in chronic Achilles tendinopathy (AT).

Healthy males with AT will be randomly assigned to either 1) HVI with steroid (50 mls;10 mls 0.5% bupivacaine hydrochloride and 20 mg of Depomedrol followed by 40 ml saline) or 2) HVI without steroid (50 mls;10 mls 0.5% bupivacaine hydrochloride followed by 40 ml saline).

All subjects will perform a 12-wk eccentric training program with further eccentric training 3 times per week from week 12 to week 24.

Clinical examinations and ultrasound will be performed at baseline (before treatment) with follow-ups after 6 weeks, 12 weeks and again after 24 weeks prior to baseline to see any possible changes and differences between the two groups.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Bispebjerg Hospital
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Clinically and ultrasound diagnosed unilateral mid-tendinous Achilles tendinopathy.

• Symptoms > 3 month

Exclusion Criteria:

• Bilateral achilles tendinopathy

• Insertional tendinopathy

• Steroid injections < 12 month

• Diabetes or cardiovascular disease

• Smoking

• Treatment with fluoroquinolones < 6 month