The Effect of Granulocyte Colony Stimulating Factor (G-CSF) on Myocardial Function After Acute Anterior Myocardial Infarction, a Prospective Double Blind Randomized Placebo Controlled Study

• Status: Completed
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators applied G-CSF to patients 2 weeks after acute anterior MI and successful PCI to evaluate the efficacy and safety of G-CSF in improving myocardial function as cytokine which improve inflammation and mobilize stem cells from bone marrow for regeneration of myocardium.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shiraz University of Medical Sciences
• Treatments: Lenograstim

Criteria

Inclusion Criteria:

• First anterior myocardial infarction.

• Low systolic ventricular function.

Exclusion Criteria:

• Bleeding tendency

• Contraindication to G-CSF

• Cardiogenic shock

• Hemodynamic instability

• Hepatic or renal disease

• Multivessel disease