The Effect of Gabapentin on the Sensation and Impact of Tinnitus

• Status: Completed
• Trial end date: 2005-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluated the effectiveness of gabapentin in treating tinnitus in two populations:

Tinnitus with associated acoustic trauma and tinnitus without associated acoustic trauma. The hypothesis was that gabapentin would decrease both subjective and objective features of tinnitus in the trauma group, but would be less effective in the non-trauma group.'

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Tinnitus Research Consortium
• Treatments: Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• non-pulsatile tinnitus present > 1 year

• Tinnitus Handicap Questionnaire score > 30

• ability to perform psychophysical matching procedure

Exclusion Criteria:

• evidence of depression

• renal insufficiency

• conductive hearing loss