The Effect of GLP-1 on the Inhibition of Glucagon Secretion
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Diabetes(both types) are recognized by high levels of glucagon in the circulation.
Glucagon is known to increase blood glucose, and might therefore contribute to the respective
diseases. Under some circumstances the gut hormone GLP-1 inhibits the glucagon secretion.
The investigators aim to identify the impact of GLP-1 on the glucagon secretion, at
increasing blood glucose levels in healthy subjects, in patients with type 2 diabetes, and in
patients with type 1 diabetes.
The investigators think that the effect of GLP-1 on the glucagon secretion might be dependent
of blood glucose levels.