The Effect of Fluorouracil Implants Regional Chemotherapy During the Surgical Treatment for Early Stage Hepatocellular Carcinoma

• Status: Unknown status
• Trial end date: 2014-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will assess the clinical efficacy and safety of fluorouracil implants regional chemotherapy during the surgical treatment for early-stage hepatocellular carcinoma.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Simcere Pharmaceutical Co., Ltd
• Collaborator: Eastern Hepatobiliary Surgery Hospital
• Treatments: Fluorouracil

Criteria

Inclusion Criteria:

• Histological diagnosis of stage I hepatocellular carcinoma

• Child-Pugh class A, B

• Radical resection is feasible

• Patients with adequate renal, hepatic, and hematologic function

• Written informed consent

Exclusion Criteria:

• Allergic to chemotherapy drugs

• No measurable lesion

• Receive chemotherapy, radiotherapy or biotherapy within 30 days prior to enrollment

• Evidence of serious infection

• Renal or hepatic dysfunction, significant cardiovascular disease

• Pregnant or lactating women