The Effect of Esomeprazole and Fundoplication on Airways
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Evaluate the prevalence of bronchial responsiveness (BHR) among patients with
gastroesophageal reflux disease (GERD).
Investigate correlation between bronchial reactivity and the severity of GERD, and similarly
investigate the correlation between exhaled nitric oxide (NO) and the severity of GERD.
Compare the effects of esomeprazole 40 mg twice daily and Nissen fundoplication on bronchial
reactivity, exhaled NO, pulmonary function and quality of life.