The Effect of Ebastine/Pseudoephedrine on Subacute Cough

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether ebastine/pseudoephedrine is effective on subacute cough.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Ebastine; Ephedrine; Pseudoephedrine

Criteria

Inclusion Criteria:

• patients with subacute cough(3-8 weeks)

• age: 20-70 years

Exclusion Criteria:

• Chest X-ray abnormality(+) as a probable cause of cough

• other explainable confirmed diagnosis(+) such as acute infectious disease

• Severe cough or cough complication which needs other anti-tussive agents.

• on ACEI

• with more than three hypertensive agents

• change of hypertension medication 3 months ago

• immunocompromized host

• relative or absolute contraindication for ebastine/pseudoephedrine

1. hypersensitivity to ebastine/pseudoephedrine

2. glaucoma

3. moderate to severe hypertensive disease

4. coronary heart disease

5. hyperthyroidism

6. moderate to severe liver disease

7. benign prostate hyperplasia

8. psychological problem

9. Parkinson's disease

10. on linezolid or supposed to use it.