The Effect of Doxapram Versus Theophylline on Diaphragmatic Function
Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
Doxapram is licensed for drug-induced post-anesthesia respiratory depression , arousal effect
and return airway protective reflexes caused by barbiturates, volatile anesthetics, nitrous
oxide or benzodiazepines over dosage.
Value of theophylline to stimulate the respiratory neuronal network has been examined by
previous studies and increases the activity of respiratory muscles, including the intercostal
, transversus abdominis muscles and the diaphragm, it also has bronchodilator and
anti-inflammatory effects.