The Effect of Diclofenac Potassium Insitu Gel Vs Calcium Hydroxide as Intra-canal Medications on Post-operative Pain and Anti-bacterial Effect

• Status: Not yet recruiting
• Trial end date: 2022-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to clinically compare the post-operative pain level and antibacterial effect when using the Diclofenac Potassium Insitu gel versus calcium hydroxide as an intra- canal medication in patients with apical periodontitis.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Diclofenac

Criteria

Inclusion Criteria:

• Age between 18-45 years old.

• Males/Females.

• Lower permanent premolars with: Non-Vital pulps. Sensitive to percussion. Negative response to cold pulp tester (ethyl chloride spray1). Apical periodontitis

• Systemically healthy patients (ASA I or II).

Exclusion Criteria:

• Medically compromised patients having significant systemic disorders. (ASA III or IV).

• History of intolerance to NSAIDS.

• Patients with two or more adjacent teeth requiring endodontic treatment.

• Teeth with :

• Association with swelling or fistulous tract.

• Acute or chronic peri-apical abscess. Mobility Grade II or III.

• Pocket depth more than 5mm.

• Previous root canal therapy.

• Non-restorability

• Patients with a contraindication for the use of DFK or those known to be allergic to any of the study medications.eg. Patient with kidney problems.