The Effect of Dextrose Prolotherapy on Isokinetic Power in the Treatment of Knee Osteoarthritis

• Status: Completed
• Trial end date: 2021-06-20
• Target enrollment: 0
• Participant gender: Female

Summary

Osteoarthritis is a degenerative joint disease characterized by erosion of the articular cartilage, bone hypertrophy at the margins of the joint, subchondral sclerosis, and some biochemical and morphological changes in the synovial membrane and joint capsule. It is the most common joint disease that causes serious morbidity and its prevalence increases with age. It is known that there is a decrease in the muscle strength around the knee in knee osteoarthritis, which creates difficulties in daily living activities.

Prolotherapy is a regenerative treatment method in the treatment of chronic musculoskeletal pain, in which an irritating solution is injected, often hypertonic dextrose, into painful ligament and tendon attachments and adjacent joint spaces.

In this study, it is aimed to investigate the effect of dextrose prolotherapy application in and around the knee on pain, range of motion and knee flexor/extensor muscle strength.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mustafa Kemal University

Criteria

Inclusion Criteria:

• Women aged 50-75 years

• 2-3 knee osteoarthritis by Kellgren Lawrence stage

• Knee pain and functional limitation

Exclusion Criteria:

• Past knee surgery

• Intra articular knee injections in the last six months

• Symptomatic heart and lung disease

• Joint contracture

• History of malignant disease

• Bleeding disorder