Overview

The Effect of Dexamethasone on Cortisol Levels in Patients Undergoing Thyroid Surgery

Status:
Withdrawn
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Many drugs are used to prevent nausea and vomiting and pain after surgery. In this study the investigators will be looking at a drug, dexamethasone, which is commonly used to prevent nausea and vomiting and pain after surgery but has other side effects. Dexamethasone is a man-made drug that is commonly used during surgery but also can affect naturally occuring hormones. In this study the investigators will be looking at dexamethasone's effect on a number of naturally occuring hormones over a twenty four hour period after thyroid surgery. The investigators hypothesize that plasma cortisol levels will be decreased following administration of dexamethasone.
Phase:
Phase 4
Details
Lead Sponsor:
St. Paul's Hospital, Canada
Treatments:
BB 1101
Cortisol succinate
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate