Overview

The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine Surgery

Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
The analgesic effect of dexamethasone is not well described, but studies have shown that dexamethasone can be a safe part of a multimodal analgesic strategy after surgery. Our purpose is to investigate if dexamethasone in combination with paracetamol and ibuprofen has an increased analgesic effect compared to paracetamol and ibuprofen alone, on postoperative pain after spine surgery. Our hypothesis is that dexamethasone can reduce postoperative pain and reduce opioidconsumption and side effects compared to placebo.
Phase:
Phase 4
Details
Lead Sponsor:
Rigshospitalet, Denmark
Collaborator:
Glostrup University Hospital, Copenhagen
Treatments:
Acetaminophen
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Ibuprofen
Morphine
Ondansetron