The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach

• Status: Recruiting
• Trial end date: 2022-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The study evaluates wether deep neuromuscular block during entire surgical procedure to the gleno-humeral joint or the proximal humerus using a deltoideo-pectoral approach results in less muscular damage to the deltoid muscle and therefore less post-operative pain and an earlier functional recovery..

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universitaire Ziekenhuizen Leuven
• Collaborator: MSD Belgium BVBA
• Treatments: Neuromuscular Blocking Agents; Rocuronium

Criteria

Inclusion Criteria:

• Adult patient undergoing elective or semi-elective surgery to the gleno-humeral joint or the proximal humerus using a deltoideo-pectoral approach

Exclusion Criteria:

• Inability to consent because of mental status

• Open injuries involving the deltoid muscle

• Previous open surgery on the shoulder joint.

• American Society of Anaesthesiologists (ASA) physical status >II

• Age <18 or >85 year old

• Body mass index (BMI) <18.5 or >35 kg/m2

• Renal insufficiency (glomerular filtration rate <40 ml/min)

• Impaired liver function (hepatic cirrhosis, cholestatic jaundice)

• Neuromuscular disease

• Pregnancy

• Breastfeeding

• Predicted difficult airway

• Patients receiving medications known to interact with neuromuscular blocking agents

• Allergy to any drug included in the anesthetic protocol