Overview

The Effect of Daily Tamsulosin 0.2mg Administration on Renal Function in Patients With Benign Prostatic Hyperplasia

Status:
Unknown status
Trial end date:
2016-06-01
Target enrollment:
0
Participant gender:
Male
Summary
The purpose of this study is to determine whether medical treatment for bladder outlet obstruction is effective in improvement of glomerular filtration rate and/or proteinuria.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
The Catholic University of Korea
Treatments:
Tamsulosin
Criteria
Inclusion Criteria:

- Men with low urinary tract symptoms aged between 40 and 80

- Estimated glomerular filtration rate < 60 or evidence of proteinuria

- Bladder outlet obstruction index > 40, Schäfer grade 2 or more, maximal flow rate
lower than 10 cc/s or postvoid residual urine > 100cc

Exclusion Criteria:

- Bladder outlet obstruction index less than 40, Schäfer grade 0 or 1, maximal flow rate
higher than 10 ml/s and postvoid residual urine less than 100cc

- Want surgical procedure

- Evidence of prostate cancer or bladder cancer

- Major depressive disorder, Dementia, Parkinson's disease or neurological deficits

- History of pelvic irradiation

- Uncontrolled diabetes mellitus or hypertension

- Symptomatic orthostatic hypotension