The Effect of Combined Iron Protocols on Perioperative Allogeneic Transfusion
Status:
RECRUITING
Trial end date:
2026-03-31
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to learn if a combined iron supplementation regimen can reduce the need for blood transfusions in adults with iron-deficiency anemia undergoing major elective cardiac surgery. The trial will also look at whether this regimen is safe and well tolerated. The main questions it aims to answer are:
Does the combined regimen lower the amount of allogeneic red blood cell transfusion needed during and after surgery?
Are there any side effects or safety concerns associated with the regimen?
Researchers will compare the combined iron supplementation (sucrose iron, erythropoietin, and vitamin C) to standard care to see if it helps reduce blood transfusions.
Participants will:
Receive either the combined regimen or standard care before surgery
Undergo major elective cardiac surgery under general anesthesia
Be monitored for blood transfusion needs and recovery up to 90 days after surgery
Phase:
NA
Details
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborators:
First Affiliated Hospital of Chongqing Medical University First Affiliated Hospital of Wenzhou Medical University Nanjing Hospital affiliated hospital of Nanjing medicine University Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University The Central Hospital of Lishui City The Fourth Affiliated Hospital of Zhejiang University School of Medicine Zhejiang Provincial People's Hospital Zhejiang University