The Effect of Colistin Inhalation on Ventilator Associated Pneumonia

• Status: Completed
• Trial end date: 2018-01-10
• Target enrollment: 0
• Participant gender: All

Summary

The study has been conducted to measure the clinical outcome of early intervention with colistin inhalation in patients with ventilator associated pneumonia suspected to have multidrug resistant gram -ve bacteria

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nourhan Hassan Osama Thuraya Mohamed
• Collaborator: Ain Shams University
• Treatments: Amikacin; Ciprofloxacin; Colistin; Gentamicins; Levofloxacin; Meropenem

Criteria

Inclusion Criteria:

• Age 18 years

Patients presenting with signs of infection 48 hours of intubation

Exclusion Criteria:

• Patients with documented bronchiectasis

Cystic fibrosis Known allergy to polymyxin. Patients presenting with chest infection or signs of infection before intubation.

Patients with creatinine clearance less than 30ml/min.