The Effect of Choline Alfoscerate on Improvement of Cognitive Function in Elderly Patients With Diabetes

• Status: Completed
• Trial end date: 2019-09-30
• Target enrollment: 0
• Participant gender: All

Summary

In this study, the investigators are going to investigate the efficacy of choline alfoscerate on improvement of cognitive function assessed by MMSE compared to plaebo.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Bundang Hospital
• Treatments: Choline

Criteria

Inclusion Criteria:

• type 2 diabetes

• baseline MMSE score 25-28

Exclusion Criteria:

• type 1 diabetes

• diabetes ketoacidosis or hyperosmolar hyperglycemic crisis

• HbA1c over than 9.0%

• MMSE less than 25

• abnormal TSH levels

• vitamin B12 deficiency

• severe infection, perioperative state, trauma

• hypopituitarism or adrenal insufficiency

• any conditions that lead to hospitalization

• chronic alcoholics within 1 year

• any drugs that can influence to cognitive function within 3 months