The Effect of Cholecalciferol in Pre-frail Elderly
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Vitamin D plays important role in musculoskeletal health and has been known to influence
immune system. Inflammaging is one of risk factors that may contribute to development of
frailty in elderly.
The purpose of this study is to determine the effects of cholecalciferol in pre-frail elderly
receiving calcium supplementation on handgrip strength, gait speed, vitamin D receptor, IGF-1
and IL-6. Fall incidence and improvement of frailty status will also be assessed.