The Effect of Carboxymetyl Starch (Oozfix) on Preventing Postoperative Complication After Gastrectomy
Status:
Recruiting
Trial end date:
2025-01-31
Target enrollment:
Participant gender:
Summary
Although the technique of radical gastrectomy had been advanced, postoperative complication
can occur in 13~25% of patient after radical gastrectomy. Pancreatic fistula and
postoperative bleeding was reported as 2~30% and 1~2%, respectively. These complications
often result fatal clinical course, so localized fibrin agent has been widely used at
postoperative surgical bed after radical gastrectomy.
Recently, natural origin polysaccharide-based carboxymetyl starch was approved as localized
coagulative, no well-designed report was adressed in gastric cancer surgery field. This agent
can formate physical barrier after application, thus can prevent microbleeding or pancreatic
fistula after gastrectomy. THIS study is single-center, non-inferiority, open-label
randomized trial that evaluates the effect of carboxymetyl starch (Oozfix) on preventing
postoperative complication after gastrectomy.