The Effect of Anesthetics Agents on Vascular Injury and Level of Syndecan-1 During Knee Surgery

• Status: Completed
• Trial end date: 2020-02-27
• Target enrollment: 0
• Participant gender: All

Summary

Ischeic reperfusion injury lead to a cellular dyfunction and increase in soluble glycocalyx of blood flow. syndecan-1 was a marker of glycocalyx.

The purpose of this study is to prove the variation of level of serum syndecan-1 between preoperative and postoperative period.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Konkuk University Medical Center
• Treatments: Anesthetics; Desflurane; Isoflurane; Propofol

Criteria

Inclusion Criteria:

• patients who was planned to undergo knee surgery.

Exclusion Criteria:

• age < 20 years old

• history of previous cancer

• history of previous peripheral vascular disease

• Emergency surgery