The Effect of Agomelatine or Fluoxentine on Heart Rate Variability in Patients With Major Depressive Disorder

• Status: Withdrawn
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Phase advance of HRV will be anticipated in agomelatine group. It is anticipated that both agomelatine and floxentine will increase HRV at the end of the treatment.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Taiwan University Hospital
• Treatments: S 20098

Criteria

Inclusion Criteria:

• Asian patients

• Male or female

• 18 to 65 years outpatients

• DSM-IV-TR criteria for Major Depressive Disorder

Exclusion Criteria:

• Patients with cardiac conditions and other physical conditions contraindicated for drug study

• Shift worker

• Patients known to be non-responders to fluoxetine treatment

• Pregnancy, or breastfeeding