The Effect of Adalimumab Plus Methotrexate (MTX) Versus Placebo Plus MTX on Cartilage in (RA) Patients
Status:
Terminated
Trial end date:
2017-09-14
Target enrollment:
Participant gender:
Summary
This study aims to compare longitudinally the effect of adalimumab plus methotrexate (MTX)
versus MTX monotherapy on cartilage GAG content, reflected by Delayed Gadolinium-enhanced
magnetic resonance imaging of cartilage (dGEMRIC) index, in patients with early progressive
rheumatoid arthritis (RA), who had not previously received any Disease modifying
antirheumatic drug (DMARD) or biologic treatment.