The Effect of Adalimumab (Humira) on Vascular Abnormalities in Rheumatoid Arthritis. A Pilot Study.
Status:
Completed
Trial end date:
2007-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether anti-inflammatory treatment with adalimumab
(Humira) reduces endothelial activation in blood vessels in patients with active rheumatoid
arthritis. Markers of endothelial activation are assessed in muscle tissue before treatment
and after 3 months, and related to other biomarkers and clinical outcomes.
Phase:
Phase 4
Details
Lead Sponsor:
Skane University Hospital
Collaborators:
Abbott Crafoord Foundation The Swedish Research Council The Swedish Rheumatism Ass