The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma
Status:
RECRUITING
Trial end date:
2037-04-30
Target enrollment:
Participant gender:
Summary
Seventy (N=70) patients with suspected pleural mesothelioma (PM) lesions referred to pleural biopsy will be recruited, and undergo an additional FAPI PET/CT at primary staging.
The FAPI PET/CT results will be compared to conventional imaging (including FDG PET/CT). The diagnostic accuracy will be determined with histopathology as reference standard.
For patients undergoing anticancer treatment (chemotherapy, immunotherapy, other treatment), an additional FAPI PET/CT and an additional FDG PET/CT will be conducted after the study subjects have completed 2-3 series of anticancer treatment. The feasabilitiy of FAPI PET/CT in response evaluation will be investigated.
All study specific analyzes will be blinded and will not influence the patient management / treatment.