The Comparison of Remimazolam With Propofol in Core Body Temperature
Status:
Completed
Trial end date:
2021-11-30
Target enrollment:
Participant gender:
Summary
1. Core body temperature is normally tightly regulated to within a few tenths of a degree.
The major thermoregulatory defences in humans are sweating, arteriovenous shunt
vasoconstriction, and shivering.
2. Inadvertent hypothermia often complicates prolonged surgery. In patients becoming
sufficiently hypothermic, reemergence of thermoregulatory vasoconstriction usually
prevents further core hypothermia.
3. The extent to which anesthetics reduce the vasoconstriction threshold depends on the
type of drug and its concentration.