The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty
Status:
Unknown status
Trial end date:
2019-09-01
Target enrollment:
Participant gender:
Summary
Post-operative bleeding in total knee arthroplasty (TKA) can result in hypovolemic shock and
unnecessity for allogenic blood transfusions. Intravenous and topical tranexamic acid (TXA)
have been well established in reducing blood loss postoperatively. However, there are lack of
data on peri-articular TXA injection during TKA. Therefore, the investigators conducted a
three-arm prospective, randomized, controlled trial to compare the effectiveness of bleeding
reduction of peri-articular TXA injections, intraarticular TXA injections and control group.