The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning

• Status: Completed
• Trial end date: 2004-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.

Details

• Lead Sponsor: China Medical University, China
• Treatments: Succimer

Criteria

Inclusion Criteria:

• Initial BLLs 100-440µg/L

• Age 3-6y

• No more than two main residences

• House cleaned (no lead contaminated)

• Normal intake history and physical

Exclusion Criteria:

• Chelation in the past 12 weeks

• Concomitant Fe deficiency(ferritin<16ng/ml)

• Hemoglobin<10.5g/dL

• Medications affecting mineral metabolism