The Cognitive Enhancing Effects of D-Cycloserine Among Non-Demented Elderly

• Status: Completed
• Trial end date: 2009-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this study is to determine whether a study medication (d-cycloserine) improves the ability of older adults to perform on tests of neuropsychological functioning. Tests of neuropsychological functioning assess attention, memory, and executive functioning skills (for example, problem-solving, planning and organizing skills). It was hypothesized that participants who received study medication would perform better on neuropsychological tests than would participants who received the sugar pill.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hartford Hospital
• Treatments: Cycloserine

Criteria

Inclusion Criteria:

• age 60 or older

• native English speaker

Exclusion Criteria:

• diagnosis of current psychiatric disorder

• substance abuse past 3 months

• cognitive impairment

• neurological disorder

• poor health or unstable medical condition

• positive toxicology screen

• current use of isoniazid

• current use of trecator

• severe renal insufficiency