The Clinical Trail Of NAFLD Treated By Traditional Chinese Medicine

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: Male

Summary

To investigate in subjects with non-alcoholic fatty liver disease the direct effects of a Chinese herb formula.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fudan University

Criteria

Inclusion Criteria:

• subjects with NAFLD(nonalcoholic fatty liver disease) (criteria of Society of Hepatology, Chinese Medical Association, 2002.10),

• aged 18-65

• alcohol consumption less than 40g/week;

• liver/spleen (L/S) ratio no more than 1 by CT scan.

Exclusion Criteria:

• ALT more than twice the upper end of the normal range

• viral hepatitis

• total parenteral alimentation or secondary liver disease such as hepatocirrhosis, autoimmune hepatitis, metabolic liver disease or drug induced liver disease

• severe cardiovascular or renal dysfunction

• Subjects with diabetes (fasting glucose more than or equal to 7.0mmol/L or postprandial glucose more than or equal to 11.1mmol/L)

• Subjects treated with statins