Overview The Childhood and Adolescent Migraine Prevention Study Status: Terminated Trial end date: 2016-01-01 Target enrollment: Participant gender: Summary The purpose of this research study is to test two medicines for migraine prevention in children and adolescents. Phase: Phase 3 Details Lead Sponsor: Children's Hospital Medical Center, CincinnatiCollaborator: National Institute of Neurological Disorders and Stroke (NINDS)Treatments: AmitriptylineAmitriptyline, perphenazine drug combinationTopiramate