The COREG And Lisinopril Combination Therapy In Hypertensive Subjects (COSMOS) Trial
Status:
Completed
Trial end date:
2008-04-01
Target enrollment:
Participant gender:
Summary
This is a randomized, double-blind, double-dummy, parallel group trial employing 15 cells of
a 4x4 factorial design (no placebo)to compare the hypertensive effects in patients with Stage
1 and Stage 2 hypertension of carvedilol (20, 40 or 80 mg daily) alone, lisinopril (10, 20 or
40 mg daily) alone, and all combinations of the doses.