The Best Treatment Strategy: Surgical vs Pharmacological to Close the Ductus Arteriosus Persistent in Preterm Infants

• Status: Unknown status
• Trial end date: 2017-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The decision to treat patent ductus arteriosus in preterm infants, varies from a conservative, medical or immediate surgical treatment; although, at present, there is some controversy about this decision. This study aims to determine the efficacy and safety of surgical versus pharmacological treatment of patent ductus arteriosus in preterm infants.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital General Naval de Alta Especialidad - Escuela Medico Naval
• Treatments: Acetaminophen; Indomethacin

Criteria

Inclusion Criteria:

• Preterm infants

• Preterm infants hospitalized in the Neonatal Intensive Care Unit with a diagnosis of patent ductus arteriosus

Exclusion Criteria:

• Preterm infants with supportive treatment and / or drug prior to patent ductus arteriosus in another medical unit

• Preterm infants diagnosed with heart disease associated complex.

• Preterm infants with associated disease (not hemodynamic or cardiovascular) and its impact on his state of health prior to drug treatment and / or surgery

• Preterm infants with contraindications to pharmacological and / or surgery treatment

• Newborns diagnosed with patent ductus arteriosus but with incomplete medical records