Overview

The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil

Status:
Recruiting

Trial end date:
2025-08-01

Target enrollment:

Participant gender:

Summary

Mucocutaneous leishmaniasis is endemic in the central region of Brazil and other countries worldwide. The standard treatment with meglumine antimoniate has a high rate of important adverse effects. This interventional study consists in a randomized clinical trial to access efficacy and safety of the association of miltefosine and pentoxifylline compared to meglumine antimoniate and pentoxifyline.

Phase:

Phase 2

Details

Lead Sponsor:

University of Brasilia

Treatments:

Meglumine Antimoniate
Miltefosine
Pentoxifylline