Overview

The Anti-CTLA-4 Monoclonal Antibody Tremelimumab in Malignant Mesothelioma

Status:
Unknown status
Trial end date:
2015-01-01
Target enrollment:
Participant gender:
Summary
RATIONAL: Preliminary results fron the Study MESOT-TREM-2012 indicate a promising activity of tremelimumab in malignant mesothelioma (MM) patients. PURPOSE: The proposed study MESOT-TREM-2012 aims to explore the efficacy of a more intensive schedule of treatment with tremelimumab in 29 MM patients. Subjects will receive investigational product every 4 weeks (wks) for 6 doses, followed by doses every 12 wks until confirmed disease progression.
Phase:
Phase 2
Details
Lead Sponsor:
Azienda Ospedaliera Universitaria Senese
Collaborator:
MedImmune LLC
Treatments:
Antibodies
Antibodies, Monoclonal
Immunoglobulins
Tremelimumab