The Anesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Status:
Not yet recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
Cortical spreading depolarisations are pathological depolarisation waves that occur
frequently after severe acute brain injury and has been associated with poor outcome.
S-ketamine has been shown to inhibit cortical spreading depolarisations. The aim of the
present study is to examine the efficacy and safety of using S-ketamine for treatment of
patients with severe acute brain injury, as well as the feasibility of the trial design.
Phase:
Phase 4
Details
Lead Sponsor:
Rigshospitalet, Denmark
Collaborator:
Copenhagen Trial Unit, Center for Clinical Intervention Research