The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution

• Status: Completed
• Trial end date: 2010-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective of this study is to study the acute effects of angiotensin-converting enzyme inhibitor (ACEI) on systemic, pulmonary and cerebral blood flow in post bidirectional cavopulmonary connection (BCPC) patients.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Hospital for Sick Children
• Treatments: Angiotensin-Converting Enzyme Inhibitors; Enalapril; Enalaprilat; Enzyme Inhibitors

Criteria

Inclusion Criteria:

• BCPC patients at time of routine pre-Fontan catheterization

• Patients between the ages of 2 months and 5 years old

Exclusion Criteria:

• Patients who have had ACEI therapy within 24 hours of the procedure