Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma
Status:
Completed
Trial end date:
2006-03-21
Target enrollment:
Participant gender:
Summary
RATIONALE: Thalidomide may stop the growth of malignant glioma by stopping blood flow to the
tumor. Drugs used in chemotherapy, such as procarbazine, work in different ways to stop tumor
cells from dividing so they stop growing or die. Combining thalidomide with procarbazine may
kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving thalidomide together with
procarbazine works in treating patients with recurrent or progressive malignant glioma.
Phase:
Phase 2
Details
Lead Sponsor:
Wake Forest Baptist Health Wake Forest University Health Sciences